Mayhew, D. L., Satterly III, T. F., Ware, J. S., & Mayhew, J. L. (2000). Effect on long-term creatine supplementation on liver and kidney function in college football players. Medicine and Science in Sports and Exercise, 32(5), Supplement abstract 558.

Members of a college football team, with at least two years of strength training experience, were divided into a creatine supplementation (N = 10) and a no-supplements control group (N = 23). The Cr group had been on supplements for periods of three months to four years.

Oral Cr supplementation was not associated with long-term detrimental effects on kidney or liver functions.

Implication. Creatine supplementation does not adversely effect the liver or kidneys.

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