Huey, K., & Duwe, B. (2016). Effects of a pre-exercise supplement on anaerobic power and blood lactate in males and females. Medicine & Science in Sports & Exercise, 48(5), Supplement abstract number 247.

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This study compared the effects of a supplement containing only creatine with a supplement containing creatine, beta-alanine, amino acids, caffeine, and B-vitamins on maximal anaerobic power, fatigue, and blood lactate accumulation in male and female Ss (N =20). It was hypothesized that the multiple supplement would be associated with greater anaerobic power, reduced fatigability, and reduced blood lactate levels compared to creatine-alone, with both supplements greater than placebo. Ss performed two 30-second Wingate anaerobic tests separated by a five-minute rest period, 20 minutes after consuming a placebo, creatine-alone, or a multiple-supplement in a repeated measures, blinded design. Fatigue index was quantified as relative power drop over the duration of the test. Blood lactate levels were measured before test 1 and after tests 1 and 2.

Peak anaerobic power and fatigue index did not differ between treatments for tests 1 or 2. In both genders, increases in lactate from post-test 1 to post-test 2 did not differ between treatments. Increases in lactate from pre-test 1 to post test 2 also did not differ between conditions or genders.

Implication. Creatine-alone or a multiple-supplement did not significantly increase peak anaerobic power, reduce fatigability, or buffer increases in lactate with repeated anaerobic power tests when compared to a placebo supplement.

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