Kilduff, L. P., Vidakovic, P., Cooney, G., Twycross-Lewis, R., Amuna, P., Parker, M., Paul, L., & Pitsiladis, Y. P. (2002). Effects of creatine on isometric bench-press performance in resistance-trained humans. Medicine and Science in Sports and Exercise, 34, 1176-1183.

Resistance-trained men were formed into two groups, one taking creatine (N = 21), the other a placebo (N = 11). Treatment lasted for five days. Ss in the creatine group were classified as "responders" or "non-responders" depending upon how they reacted to the creatine supplementation. [This action recognizes that not all athletes will respond to creatine supplementation.]

When responders and non-responders were included in comparisons, some comparisons with the placebo group were declared as non-significant. However, when responders alone were compared with placebo, differences emerged. Responders increased in body weight, fat-free body mass, and peak force and total force in a repeated maximal isometric bench-press test.

Implication. Five days of creatine supplement affects body composition and strength measures in resistance trained men who respond to creatine.

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